Welcome to
The Lynch Lab!
At The Lynch Lab, we are dedicated to exploring the intricate connections between obesity, diet, and immune cell functions.
Our research focuses on understanding how these factors influence innate immune cells, including invariant natural killer T (iNKT) cells, natural killer (NK) cells & gamma delta T cells.
In addition to our primary research, we investigate the critical role of the immune system in regulating metabolism and body weight. We pay special attention to the local immune system within adipose tissue, studying its impact in both mice and humans.
Meet The Team
Lydia Lynch, PhD
Principle Investigator
Professor, Molecular Biology, Princeton
Full Member, Ludwig Cancer Research Institute, Princeton Branch
Martin Brennan
PhD student
Project: Characterisation of murine CD3+, CD4-, CD8-double negative T cells in homeostasis and cancer
Science Interests: T cell biology, cytokines, cancer immunology, gut mucosa.
Interests/Hobbies: I love travelling and exploring new places, keeping up with tv shows & movies, gym & fitness, and my newfound hobby, stage acting.
Favourite Cell: I have a soft spot for all unconventional T cells!
Thomas Atkins
Graduate Student
Project: Co-advised between Julien Ayroles and Lydia Lynch, Thomas is interested in understanding immune variation—between populations, between individuals, and between cells—and its consequences.
Interests/Hobbies: I enjoy cooking, playing D&D and videogames with friends, and visiting art museums!
Favourite Cell: What even is a cell type, anyway?
Claire McIntyre
Postdoctoral Fellow
(co-mentored by Dr Alison Ringel at The Ragon Institute, MIT)
Project: Understanding lipid metabolic pathways that regulate gamma delta T cell function and how we can target these therapeutically.
Interests/Hobbies: Cycling and baking
Favourite Cell: Has to be gamma delta T cells of course!
Kristin DePeaux
Postdoc
Project: Understanding how obesity and host metabolism affect the tumor microenvironment, specifically CD8+ T cell fate and function.
Interests/Hobbies: Hiking & crafting
Favourite Cell:Cytotoxic T cell & Treg
Matt Fischer
Postdoc
Project: I am interested in understanding how γδ T cell-derived IL-17 coordinates adipose tissue homeostasis
Interests/Hobbies: I enjoy hearing stories and playing games, and I love it when these two things intersect
Favourite Cell: γδ T cells
Yu-San Kao
Postdoctoral Research Associate
Project: My research interest is investigating how metabolic regulation determines the fate and function of T cells. My research here focusses on studying the role of lipid droplets and type 17 signature genes in γδ T cells.
Interests/Hobbies: Badminton, Travel, Drinking bubble tea
Favourite Cell: γδT17 cells
Brittany Bamonte
Project: My main focus is our mice. I perform injections and collect data from the laboratory mice in order to help my lab-mates meet their research goals. I hope to continue to improve in all areas involving the mice to better assist everyone!
Interests/Hobbies: Drawing, writing, and reading.
